Researchers at King's College London found that the drug Tideglusib stimulates the stem cells contained in the pulp of teeth so that they generate new dentine -- the mineralised material under the enamel.
Tideglusib switches off an enzyme called GSK-3 which prevents dentine from carrying on forming. Scientists showed it is possible to soak a small biodegradable sponge with the drug and insert it into a cavity, where it triggers the growth of dentine and repairs the damage within six weeks.
Professor Paul Sharpe, lead author of the study, of the Dental Institute, from King's College London, said: "The simplicity of our approach makes it ideal as a clinical dental product for the natural treatment of large cavities, by providing both pulp protection and restoring dentine. "In addition, using a drug that has already been tested in clinical trials for Alzheimer's disease provides a real opportunity to get this dental treatment quickly into clinics."
Based on the "previouslies" in this post (ten years ago, seven years ago, three years ago), I'm starting to suspect the hand of the powerful Oral Decay Lobby in suppressing this technology.