Gut Fermentation Syndrome is described as a syndrome whereby patients become intoxicated without ingesting alcohol. In addition to the term Auto-Brewery, this syndrome has also been called Drunkenness Disease and Endogenous Ethanol Fermentation. The underlying mechanism is thought to be an overgrowth of yeast in the gut whereby the yeast ferments carbohydrates into ethanol.
A 61 years old male, presented in January of 2010 with at least a five-year history of unexplained intoxication. [...] In November of 2009, the subject was taken to the Emergency room on a day when he had not ingested alcohol. In the ER, his blood alcohol concentration was 371 (0.37%). He was admitted to the hospital for 24-hour observation and treated for severe alcohol intoxication. [...]
In April of 2010 the patient was admitted to the hospital for a 24-hour observation period. [...] At one point during the afternoon, the patient's BAC rose to 120 mg/dl (0.12% per breathalyzer) in this controlled situation.
A Case Study of Gut Fermentation Syndrome with Saccharomyces cerevisiae as the Causative Organism