A Simple and Convenient Synthesis of Pseudoephedrine From N-Methylamphetamine

Journal of Apocryphal Chemistry, Feb 2012:

A quick search of several neighborhoods of the United States revealed that while pseudoephedrine is difficult to obtain, N-methylamphetamine can be procured at almost any time on short notice and in quantities sufficient for synthesis of useful amounts of the desired material. Moreover, according to government maintained statistics, N- methylmphetamine is becoming an increasingly attractive starting material for pseudoephedrine, as the availability of N- methylmphetamine has remained high while prices have dropped and purity has increased [2]. We present here a convenient series of transformations using reagents which can be found in most well stocked organic chemistry laboratories to produce psuedoephedrine from N-methylamphetamine.

"Institute for Theoretical Experiments, Department of Chemistry, Miskatonic University."

Previously, previously.

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13 Responses:

  1. Grey Hodge says:

    Am I the only one hearing the anti-DRM arguments echoed here? It's easier to get meth and make it into sudafed than to buy sudafed/it's easier to pirate the movie than buy it.

  2. DzM says:

    While flying back to the Bay Area from Vancouver last week the girl in the seat behind me began having some kind of allergy attack. Dude-guy in the seat next to me volunteered pink pills from a small container (I assumed it to be pseudoephedrine). This earned him free wine for the rest of the flight.

    I can only imagine how stoned he must have been by the end of the flight.

  3. Dan says:

    I definitely did a double take on this...it took me a good two minutes to get the joke (or that it even was a joke). Pretty funny, in spite of my slow uptake.

  4. John Bloom says:

    Science imitates comment threads?

    For people joining our discussion, already in progress:
    In 2005, fgmr said, "I should go look for a recipe for making sudafed from meth . . . "
    And earlier this year, Dwyer said (jokingly?), "I've taken to buying meth on street corners, then taking it home and cooking it back down into effective cold medicine."

    • jwz says:

      Yeah but not everybody has it in them to take a one-liner gag like that and overthink it to such a degree!

      • John Bloom says:

        Actually, the joke's on me. I didn't RTFA and didn't even realize this was a joke before posting that comment. Bravo to guys who wrote this.

    • Jokingly? Effective cold medicine is not something to joke about. Unless we're talking about that phenylephrine crap. That shit's a joke.