The UCLA AIDS Institute scientists genetically altered HIV and folded it into an envelope made of another virus called sindbis, which typically infects insects and birds. That turned the altered HIV into a missile that hunted down metastasized melanoma cells in the lungs of living mice.
"People might wonder if it's scary to use HIV as a therapy," said Irving Chen, who led the UCLA team. "But in actuality we have completely removed 80 percent of the virus. So really it's just a carrier."
Researchers at UCLA have tweaked HIV to create a gene therapy that attacks cancer tumors in mice.
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